Publications

Artz ME, Grewal HS, Zhang Y, Johnson PB, Saki M, Schreuder N, Brooks ED, Park J. Operational Improvement of a Proton Therapy System From Reduced Energy Layer Switching Time. International Journal of Particle Therapy. 2025 Jun 1;16:100742.

Brooks ED, Sio TT, Ning MS, Morris CG, Mendenhall NP, Turner M, Vergara NK, Palmer M, Artz ME. Independent Review Organization and Proton Therapy: Multistate Analysis and Legal Procedural Strategies. Int J Part Ther. 2025 Feb 17;15:100741.

Johnson PB, Bradley J, Lampotang S, Jackson A, Lizdas D, Johnson W, Brooks E, Vega RB, Mendenhall N. First-in-human trial using mixed-reality visualization for patient setup during breast or chest wall radiotherapy. Radiation Oncology. 2024 Nov 18;19(1):163.

Saki M, Grewal H, Artz M, Willoughby TR, Park J, Brooks E, Getman N, Senterfitt A, Johnson P. Navigating complexities: leadless pacemaker management in proton therapy for a pacemaker-dependent bilateral breast cancer patient. International Journal of Particle Therapy. 2024 Sep 1;13:100112.

Artz ME, Brooks ED. Radiation Toxicity in MDA5+ and PL7-Positive Dermatomyositis: Heightened Risk in Autoimmune Subtypes. International Journal of Particle Therapy. 2024 Dec 1;14:100109.

Kumar SS, Bradley JA, Mendenhall NP, Vega RB, Brooks ED, Okunieff PG, Giap F, Burchianti T, Daily K, Heldermon CD, Galochkina Z. Effects on Lung Tissue After Breast Cancer Radiation: Comparing Photon and Proton Therapies. International Journal of Particle Therapy. 2024 Mar 1;11:100006.

Brooks ED, Deladisma AM, Morris CG, Mobley EM, Neumayer LA, Bradley JA, Vega RB. Axillary Surgery for Chemoresidual (ypN-Positive) Nodal Disease. JAMA oncology. 2024 May 16.

Brooks ED, De Leo AN. Solving access to lung cancer care across Europe. The Lancet Regional Health–Europe. 2024 Mar 1;38.

Bradley JA, Gracie J, Mailhot Vega RB, Brooks ED, Burchianti T, Oladeru OT, Liang X, Mendenhall NP. Proton Therapy in the Treatment of Men with Breast Cancer. International Journal of Particle Therapy. 2023 Nov 1;10(2):94-104.

Brooks ED. Safe and effective systemic therapy for early-stage non-small-cell lung cancer. The Lancet. 2023 Jul 18.

Giap F, Ma SJ, Oladeru OT, Hong YR, Yu B, Mailhot Vega RB, Brooks ED, Singh AK, Okunieff PG, Mendenhall NP, Bradley JA. Palliative care utilization and racial and ethnic disparities among women with de novo metastatic breast cancer in the United States. Breast Cancer Research and Treatment. 2023 Jun 3:1-8.

Brooks ED, Giap F, Cassidy V, Ning MS, Robbert B, Redding P, Palmer M, Turner LM, Mendenhall WM, Klein S, Mendenhall NP. Strategic Operational Redesign Improves Prior Authorization Access: A Validation Study. 2023 Accepted to IJPT.

Brooks ED, Mailhot Vega RB, Vivers E, Burchianti T, Liang X, Spiguel LR, Jasra B, Mendenhall NP, Oladeru OT, Bradley JA. Proton Therapy for Bilateral Breast Cancer Maximizes Normal-Tissue Sparing. International Journal of Particle Therapy. 2023;9(4):290-301.

Bradley JA, Liang X, Mailhot Vega RB, Liu C, Brooks ED, Burchianti T, Viviers E, Dagan R, Oladeru OT, Morris CG, Mendenhall NP. Incidence of Rib Fracture following Treatment with Proton Therapy for Breast Cancer. International Journal of Particle Therapy. 2023;9(4):269-78.

Vega RB, Wang S, Brooks ED, Oladeru OT, Lockney NA, Spiguel LE, MacDonald SM, Mamounas EP, Mendenhall NP, Okunieff PG, Lee JH. Evaluating Regional Nodal Irradiation Allocation and Association with Oncologic Outcomes in NSABP B-18, B-27, B-40, and B-41. International Journal of Radiation Oncology* Biology* Physics. 2022 Mar 29.

De Leo AN, Dagan R, Amdur RJ, Yeung AR, Li J, Brooks ED, Gilbo P, Gomez D, Chang JY, Ning M. How Three Academic Centers Prescribe SBRT for Primary Lung Cancer. Practical Radiation Oncology. 2022 Feb 24.

Looi WS, Bradley JA, Liang X, Shaw CM, Leyngold M, Vega RB, Brooks ED, Rutenberg MS, Spiguel LR, Giap F, Mendenhall NP. Hyperfractionated-Accelerated Reirradiation with Proton Therapy for Radiation-Associated Breast Angiosarcoma. International journal of particle therapy. 2022;8(4):55-67.

Brooks ED, Wang X, De B, Verma V, Williamson TD, Hunter R, Mohamed AS, Ning MS, Zhang X, Chang JY. An algorithm for thoracic re-irradiation using biologically effective dose: a common language on how to treat in a “no-treat zone”. Radiation Oncology. 2022 Dec;17(1):1-1.

Mendenhall WM, Brooks ED, Smith S, Morris CG, Bryant CB, Henderson RH, Nichols Jr RC, McIntyre K, Klein SL, Mendenhall NP. Insurance Approval for Definitive Proton Therapy for Prostate Cancer. International Journal of Particle Therapy. 2022;8(3):36-42.

Herremans KM, Cribbin MP, Riner AN, Neal DW, Hollen TL, Clevenger P, Munoz D, Blewett S, Giap F, Okunieff PG, Mendenhall NP, Bradley JA, Mendenhall WH, Mailhot-Vega RB, Brooks ED, Daily KC, Heldermon CD, Marshall JK, Hanna MW, Leyngold MM, Virk SS, Shaw CM, Spiguel LR. Five-Year Breast Surgeon Experience in LYMPHA at Time of ALND for Treatment of Clinical T1–4N1–3M0 Breast Cancer. Annals of surgical oncology. 2021 Oct;28(10):5775-87.

Brooks ED, Fang P, Pinnix CC. Salvage radiotherapy for primary refractory and relapsed diffuse large B-Cell lymphoma. The British Journal of Radiology. 2021 Nov 1;94(1127):20210360.

Huang D, Frank SJ, Verma V, Thaker NG, Brooks ED, Palmer MB, Harrison RF, Deshmukh AA, Ning MS. Cost-Effectiveness Models of Proton Therapy for Head and Neck: Evaluating Quality and Methods to Date. International journal of particle therapy. 2021;8(1):339-53.

Liu SM, Brooks ED, Rubin ML, MD Anderson Cancer Center Radiation Oncology Fellows Consortium, Grosshans DR, Frank SJ, McAleer MF, McGovern SL, Paulino AC, Woodhouse KD. Referral Patterns and Treatment Delays in Medulloblastoma: A Large Academic Proton Center Experience. International Journal of Particle Therapy. 2021;7(3):1-0.

Brooks ED, Ning MS, Palmer MB, Gunn GB, Frank SJ, Shah AK. Strategic Operational Redesign for Successfully Navigating Prior Authorization Barriers at a Large-Volume Proton Therapy Center. JCO Oncology Practice. 2020 Jul:JOP-19.

Nantavithya C, Gomez DR, Chang JY, Mohamed AS, Fuller CD, Li H, Brooks ED, Gandhi SJ. An improved method for analyzing and reporting patterns of in-field recurrence after stereotactic ablative radiotherapy in early-stage non-small cell lung cancer. Radiotherapy and Oncology. 2020 Apr 1;145:209-14.

Ayoub Z, Ning MS, Brooks ED, Kang J, Welsh JW, Chen A, Gandhi S, Heymach JV, Vaporciyan AA, Chang JY. Definitive Management of Presumed Synchronous Early-Stage Non-Small Cell Lung Cancers: Outcomes and Utility of Stereotactic Ablative Radiotherapy. International Journal of Radiation Oncology* Biology* Physics. 2020 Feb 7.

Brooks ED, Verma V, Senan S, De Baere T, Lu S, Brunelli A, Chang JY, on behalf of the IASLC Advanced Radiation Technology Committee. Salvage Therapy for Locoregional Recurrence After SABR for Early-Stage NSCLC. Journal of Thoracic Oncology. 2019.

Kang J, Ning MS, Feng H, Li H, Bahig H, Brooks ED, Welsh JW, Ye R, Miao H, Chang JY. Predicting 5-Year Progression and Survival Outcomes for Early-Stage Non-Small Cell Lung Cancer Treated with Stereotactic Ablative Radiotherapy: Development and Validation of Robust Prognostic Nomograms. International Journal of Radiation Oncology• Biology• Physics. 2019 Oct 3.

Jarrett BY, Vantman N, Mergler RJ, Brooks ED, Pierson RA, Chizen DR, Lujan ME. Dysglycemia, Not Altered Sex Steroid Hormones, Affects Cognitive Function in Polycystic Ovary Syndrome. Journal of the Endocrine Society. 2019 Jul 30;3(10):1858-68.

Verma V, Ludmir EB, Mesko SM, Brooks ED, Augustyn A, Milano MT, Lin SH, Chang JY, Welsh JW. Commercial Insurance Coverage of Advanced Radiation Therapy Techniques Compared With American Society for Radiation Oncology Model Policies. Practical radiation oncology. 2019 Aug 22.

Brooks ED, Ning MS, Verma V, Zhu XR, Chang JY. Proton therapy for non-small cell lung cancer: the road ahead. Transl Lung Cancer Res, 2019.

Jarrett BY, Brink HV, Brooks ED, Hoeger KM, Spandorfer SD, Pierson RA, Chizen DR, Lujan ME. Impact of right–left differences in ovarian morphology on the ultrasound diagnosis of polycystic ovary syndrome. Fertility and Sterility. 2019 Aug 5.

Jarrett BY, Vantam N, Mergler RJ, Brooks ED, Pierson RA, Chizen DR, Lujan ME. Dysglycemia, and not altered sex steroid hormones, impacts cognitive function in polycystic ovary syndrome. Journal of the Endocrine Society. 2019.

Brooks ED, Verma V, Chang JY. Does Pathologic Response Equate to Clinical Response Following SABR for Early-Stage NSCLC?. Frontiers in Oncology. 2019.

Sun AH, Eilbott J, Chuang C, Yang JF, Brooks ED, Beckett J, Steinbacher DM, Pelphrey K, Persing JA. An Investigation of Brain Functional Connectivity by Form of Craniosynostosis. J Craniofac Surg. 2019.

Verma V, Wegner RE, Brooks ED, Miccio JA, Kann BH, Finley GG, Raj MS, Grover S, Mohindra P, Simone CB 2nd. Chemotherapy Versus Supportive Care for Unresected Malignant Pleural Mesothelioma. Clin Lung Cancer; 2019.

Li H, Verma V, Brooks ED, Feng L, Zhang T, Welsh JW, Lin SH, Gomez DR, Gandhi S, Heymach JV, Chang JY. Impact of Corticosteroid Administration on Outcomes Following Stereotactic Ablative Radiotherapy for Non-Small Cell Lung Cancer. Clinical Lung Cancer; 2019 [accepted for publication].

Cabrejo R, Lacadie C, Brooks ED, Beckett J, Sun A, Yang J, Chuang C, Eilbott J, Duncan C, Steinbacher D, Alperovich M. Understanding the Learning Disabilities Linked to Sagittal Craniosynostosis. The Journal of craniofacial surgery. 2019 Jan.

Ning MS, Gomez DR, Shah AK, Kim CR, Palmer MB, Thaker NG, Grosshans DR, Liao Z, Chapman BV, Brooks ED, Tang C, Rosenthal DI, Garden AS, Frank SJ, Gunn GB. The Insurance Approval Process for Proton Radiation Therapy: A Significant Barrier to Patient Care. IJROBP. 2018.

Brooks ED, Chang JY. Time to abandon single-site irradiation for inducing abscopal effects. Nature Reviews Clinical Oncology. 2018 Nov 6:1.

Brooks ED, Sun B, Feng L, et al. Association of Long-term Outcomes and Survival With Multidisciplinary Salvage Treatment for Local and Regional Recurrence After Stereotactic Ablative Radiotherapy for Early-Stage Lung Cancer. JAMA Network Open. 2018;1(4):e181390. doi:10.1001/jamanetworkopen.2018.1390

CUSHMAN, T.R., VENIGALLA, S., BROOKS, E.D., LIN, C. and VERMA, V., 2018. Utilization of Neoadjuvant Intensity-modulated Radiation Therapy for Rectal Cancer in the United States. Anticancer research, 38(5), pp.2923-2927.

Chuang, C., Rolison, M., Yang, J.F., Brooks, E.D., Hashim, P.W., Travieso, R., Terner, J., Steinbacher, D.M., Landi, N., Stavropoulos, K.K. and Mayes, L.C., 2018. Normalization of Speech Processing After Whole-Vault Cranioplasty in Sagittal Synostosis. Journal of Craniofacial Surgery, 29(5), pp.1132-1136.

Verma, V., Surkar, S.M., Brooks, E.D., Simone, C.B. and Lin, C., 2018. Chemoradiotherapy versus chemotherapy alone for unresected nonmetastatic gallbladder cancer: National Practice Patterns and Outcomes. Journal of the National Comprehensive Cancer Network, 16(1), pp.59-65.

Brooks ED, Beckett JD, Yang J, Timberlake AT, Sun, AH, Chuang C, Persing JA. The Etiology of Neuromaldevelopment in Craniosynostosis: A Working Hypothesis. J Craniof Surg. 2017. (Accepted for publication.)

Brooks ED, Chang JY. Editorial response: “Stereotactic Ablative Radiotherapy vs. Sublobar Resection for Non-Small Cell Lung Cancer: Choosing the Right Patients (an editorial)”. AME Medical Journal 2.5, 2017.

Schoenhals JE, Seyedin SN, Anderson C, Brooks ED, Li YR, Younes AI, Niknam S, Li A, Barsoumian HB, Cortez MA, Welsh JW. Uncovering the immune tumor microenvironment in non-small cell lung cancer to understand response rates to checkpoint blockade and radiation. Transl Lung Cancer Res. 2017 Apr; 6(2):148-158.

Brooks ED, Schoenhals JE, Tang C, Micevic G, Gomez DR, Chang JY, Welsh JW. Stereotactic Ablative Radiation Therapy Combined With Immunotherapy for Solid Tumors. Cancer J. 2016 Jul-Aug; 22(4):257-66.

Brooks ED, MD, MHS, Bing Sun, MD, Lina Zhao, MD, Ritsuko Komaki, MD, Zhonxing Liao, MD, Melenda Jeter, MD, James W. Welsh, MD, Michael S. O’Reilly, MD, PhD, Daniel R. Gomez, MD, Stephen M. Hahn, MD, John V. Heymach, MD, PhD, David C. Rice, MD, Joe Y. Chang, MD, PhD. Stereotactic Ablative Radiation Therapy is Highly Safe and Effective for Elderly Patients With Early-stage Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys. 2016 Dec 21.

Sun, Bing, Brooks ED, Ritsuko Komaki, Zhongxing Liao, Melenda Jeter, Mary McAleer, Peter A. Balter et al. “Long-Term Outcomes of Salvage Stereotactic Ablation Radiotherapy for Isolated Lung Recurrence of Non-Small-Cell Lung Cancer: A Phase II Clinical Trial.” Journal of Thoracic Oncology (2017).

Sun B, Brooks ED, Komaki RU, Liao Z, Jeter MD, McAleer MF, Allen PK, Balter PA, Welsh JD, O’Reilly MS, Gomez D, Hahn SM, Roth JA, Mehran RJ, Heymach JV, Chang JY. 7-year follow-up after stereotactic ablative radiotherapy for patients with stage I non-small cell lung cancer: Results of a phase 2 clinical trial. Cancer. 2017 Mar 27.

Yang, Jenny F., Brooks ED, Peter W. Hashim, Hannah S. Reuman, Roberto Travieso, Jordan Terner, Linda C. Mayes, Derek M. Steinbacher, John A. Persing, and James C. McPartland. “The Severity of Deformity in Metopic Craniosynostosis Is Correlated with the Degree of Neurologic Dysfunction.” Plastic and reconstructive surgery 139, no. 2 (2017): 442-447.

Timberlake AT, Choi J, Zaidi S, Lu Q, Nelson-Williams C, Brooks ED, Bilguvar K, Tikhonova I, Mane S, Yang JF, Sawh-Martinez R, Persing S, Zellner EG, Loring E, Chuang C, Galm A, Hashim PW, Steinbacher DM, DiLuna ML, Duncan CC, Pelphrey KA, Zhao H, Persing JA, Lifton RP. Two locus inheritance of non-syndromic midline craniosynostosis via rare SMAD6 and common BMP2 alleles. Elife. 2016 Sep 8; 5. pii: e20125.

Brooks ED, Yang Y, Beckett JS, Lacadie C, Scheinost D, Persing S, Zellner EG, Oosting D, Keifer C,  Friedman HE, Vander Wyk B, Jou RJ, Sun H, Gary C, Duncan CC, Constable TR, Pelphrey KA, Persing JA. Normalization of Brain Morphology after Surgery in Sagittal Craniosynostosis. J Neurosurg Pediatr 2015.

Brooks ED*, Beckett BS*, Lacadie C, Vander Wyk B, Jou R, Steinbacher DM, Constable T, Pelphrey KA, Persing JA. Altered Brain Connectivity in Sagittal Craniosynostosis. J Neurosurg Pediatr 2014, 13(6):690-8. *Co-first author.

Yang JF, Brooks ED, Hashim PW, Travieso R, Terner J, Reuman HS, Persing SM, Zellner EG, Martinez-Sawh R, Levy EJ, Law K, Mayes LC, Duncan C, Steinbacher DM, Persing JA, McPartland JC. Neurocognitive Effects of Metopic Synostosis Based on Severity of Deformity. Plast Reconstr Surg 2015, 136(4 Suppl):42-3.

Forte AJ, Steinbacher DM, Persing JA, Brooks ED, Andrew TW, Alonso N. Orbital Dysmorphology in Untreated Children With Crouzon and Apert Syndromes. Plast Reconstr Surg 2015 ( Accepted.)

Hashim PW, Brooks ED, Persing JA, Reuman H, Naples A, Travieso R, Terner J, Steinbacher D, Landi N, Mayes L, McPartland JC. Direct brain recordings reveal impaired neural function in infants with single-suture craniosynostosis: A future modality for guiding management? J Craniofac Surg 2015, 26(1):60-3.

Forte AJ, Alonso N, Persing JA, Pfaff MJ, Brooks ED, Steinbacher DM. Analysis of Midface Restrusion in Crouzon and Apert Syndrome. Plast Reconstr Surg 2014, 134(2):285-93.

Christ JP, Vanden Brink H, Brooks ED, Pierson RA, Chizen DR, Lujan ME. Ultrasound features of polycystic ovaries relate to degree of reproductive and metabolic disturbance in polycystic ovary syndrome. Fertil Steril. 2015 Mar;103(3):787-94.

Clark NM, Podolski AJ, Brooks ED, Chizen DR, Pierson RA, Lehotay DC, Lujan ME. Prevalence of Polycystic Ovary Syndrome Phenotypes Using Updated Criteria for Polycystic Ovarian Morphology: An Assessment of Over 100 Consecutive Women Self-reporting Features of Polycystic Ovary Syndrome. Reprod Sci  2014, 11; 21(8):1034-1043.

Christ JP, Willis AD, Brooks ED, Vanden Brink H, Jarrett BY, Pierson RA, Chizen DR, Lujan ME. Follicle number, not assessments of the ovarian stroma, represents the best ultrasonographic marker of polycystic ovary syndrome. Fertility and sterility 2014, 101(1): 280-287.

Lujan ME, Jarrett BY, Brooks ED, Reines JK, Peppin AK, Muhn N, Haider E, Pierson RA, Chizzen DR: Updated ultrasound criteria for polycystic ovary syndrome: reliable thresholds for elevated follicle population and ovarian volume. Human Reproduction 2013, 28(5), 1361-1368.

Lujan ME, Brooks ED, Kepley AL, Chizen DR, Pierson RA, Peppin AK: Grid analysis improves reliability in follicle counts made by ultrasonography in women with polycystic ovary syndrome. Ultrasound Med Biol 2010, 36(5): 712-718.